Civil Services Prep

Prelims 2019 · Science and Technology · Question 49

What is Cas9 protein that is often mentioned in news?

  1. A molecular scissors used in targeted gene editing
  2. A biosensor used in the accurate detection of pathogens in patients
  3. A gene that makes plants pest-resistant
  4. A herbicidal substance synthesized in genetically modified crops

Answer

A molecular scissors used in targeted gene editing

  • (a) A molecular scissors used in targeted gene editingCorrect. Cas9 is an enzyme used in the CRISPR-Cas9 system to cut DNA at specific sites, so it is called a molecular scissor.
  • (b) A biosensor used in the accurate detection of pathogens in patientsIncorrect. CRISPR-based diagnostics exist, but Cas9 itself is primarily known for gene editing, not as a biosensor.
  • (c) A gene that makes plants pest-resistantIncorrect. Cas9 is a protein/enzyme, not a gene conferring pest resistance.
  • (d) A herbicidal substance synthesized in genetically modified cropsIncorrect. Cas9 is not a herbicide or a chemical synthesized in GM crops; it is a DNA-cutting protein.

Answer: (a)

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